We have reviewed 35 cycles in 27 patients who underwent IVF and ET with reasonable indications from March 1992 to February 1993. The method of ovarian hyperstimulation were FSH/hMG/hCG(N=10), GnRH agonist(N=24), C.C./hMG/hCG(N=1).
The results were as follows ;
1) The mean age of patients was 33.04±4.17 and mean duration of infertility was 5.52±3.37 years.
2) Major indications for IVF and ET were tubal factor(77.80%), peritoneal factor(18.50%), and unexplained infertility(3.70%).
3) In the past history of patients, there were previous ectopic pregnancy in 5 cases(17.24%), previous tuboplasty in 5 cases(17.24%), pevic inflammatory disease in 4 cases(16.00%), and tuberculosis in 3 cases(12.00%).
4) The cancellation was only one case in FSH/hMG/hCG group.
5) The timing of hCG administration in FSH/hMG/hCG group was 9.56±1.50 day and GnRH-a group was 9.17±0.99 day.
6) The mean numbers of follicles larger than 16mm were 6.78±4.71 in FSH/hMG/hCG group and 5.33±3.82 in GnRH-a group.
7) The mean numbers of oocyte aspirated were 6.44±3.17 in FSH/hMG/hCG group and 5.54±2.27 in GnRH-a group.
8) The fertilization and cleavage rate was 59.93±33.91% in FSH/hMC/hCG group and 57.61±30.81 in GnRH-a group.
9) The mean number of embryos transfered were 4.56±3.69 in FSH/hMe/hCG group and 3.38±2.10 in GnRH-a group.
10) Pregnancy rate were 22.2% in FSH/hMG/hCC group and 25% in GnRH-a group.
11) There were 8 cases of pregnancies which consisted of two live births of 3 babies, 3 cases of ongoing pregnancies, one spontaneous abortion, two chemical pregnancies.