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Evaluation of Microparticle Enzyme Immunoassay (MEIA) (ImRx, Abbott) in the Determination of Serum Thyrotropin (TSH)

Ki Sook Hong
The Ewha Medical Journal 1993;16(1):3-8. Published online: July 24, 2015

Department of Clinical Pathology, College of Medicine, Ewha Womans University, Korea.

Copyright © 1993. Ewha Womans University School of Medicine

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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  • Microparticle enzyme immunoassay (MEIA) for thyrotropin (TSH) was evaluated and results were compared with those of immunoradiometric assay (IRMA) procedure. Coefficient of variations of within day precision was 3.8-9.6% and those of between day precision was 3.6-17.2%. Correlation between the MEIA(Y) and two site IRMA(X) was excellent (Y=1.0445X-0.1538, r=0.9948). The sensitivity of the assay (mean±2 SD of the zero standard) was 0,0158 µIU/ml. The concentration measured in 497 healthy subjects were ranged from 0.2-3 µIU/ml (mean 1.37 µIU/ml, SD 0.59).
    Conclusively, MEIA is more fully automated than IRMA, well correlated with IRMA, can be reliable method for screening test of thyroid function.

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      Evaluation of Microparticle Enzyme Immunoassay (MEIA) (ImRx, Abbott) in the Determination of Serum Thyrotropin (TSH)
      Ihwa Ŭidae chi. 1993;16(1):3-8.   Published online July 24, 2015
      DOI: https://doi.org/10.12771/emj.1993.16.1.3
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      Evaluation of Microparticle Enzyme Immunoassay (MEIA) (ImRx, Abbott) in the Determination of Serum Thyrotropin (TSH)
      Ihwa Ŭidae chi. 1993;16(1):3-8.   Published online July 24, 2015
      DOI: https://doi.org/10.12771/emj.1993.16.1.3
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      Evaluation of Microparticle Enzyme Immunoassay (MEIA) (ImRx, Abbott) in the Determination of Serum Thyrotropin (TSH)
      Evaluation of Microparticle Enzyme Immunoassay (MEIA) (ImRx, Abbott) in the Determination of Serum Thyrotropin (TSH)
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