• Contact us
  • E-Submission
ABOUT
BROWSE ARTICLES
JOURNAL POLICIES
FOR CONTRIBUTORS

Articles

Page Path

Original Article

Histomorphometry on Regenerated Muscle Fiber in the Damaged Striated Muscle

The Ewha Medical Journal 1995;18(1):45-52. Published online: July 24, 2015

Department of Orthopaedic Surgery, College of Medicine, Ewha Womans University, Korea.

Copyright © 1995. Ewha Womans University School of Medicine

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

  • 26 Views
  • 0 Download
prev next
  • The repair of striated muscle after injury by trauma or chemicals occurs simultaneously by the regeneration of disrupted muscle. Tlthough the efects of various external factors e.g. denervation, irradiation and steroid upon the repair of striated muscle injury has been previously studied, no attention has been focused on the effect of trauma and local anesthetics on the regenearted muscle fiber.
    The author induced a constant contusion injury on the calf of rats using Drop-Weight method Lidocaine and/or epinephrine was intramuscularly injected at the site of injure.
    The results of morphological and histochemical observation were as follows:
    1) The striated muscle showed histological and histochemical evidences of the healing process for 90 days.
    2) Formation of myotube appeared on 7th day and decreased on 15th day. Myotube persisted upto 30 days.
    3) The cross sectional area of the muscle fibers was measured days 30 and 90. Local anestetic injection groups showed mire muscle fiber atrophy than trauma alone groups. Muscle fibers were significantly more atrophied on day 90 in all types of fiber after injection of mixture of lidocaine and epinephrine and on type B after injection of mixture of lidocaine and epinephrine and in type B after injection of epinephrine compared to control group.
    4) Regenerative capacity of the injured muscle piber was correlated with the formation of myotubes.

Figure & Data

References

    Citations

    Citations to this article as recorded by  

      Download Citation

      Download a citation file in RIS format that can be imported by all major citation management software, including EndNote, ProCite, RefWorks, and Reference Manager.

      Format:

      Include:

      Histomorphometry on Regenerated Muscle Fiber in the Damaged Striated Muscle
      Ihwa Ŭidae chi. 1995;18(1):45-52.   Published online July 24, 2015
      Download Citation
      Download a citation file in RIS format that can be imported by all major citation management software, including EndNote, ProCite, RefWorks, and Reference Manager.

      Format:
      • RIS — For EndNote, ProCite, RefWorks, and most other reference management software
      • BibTeX — For JabRef, BibDesk, and other BibTeX-specific software
      Include:
      • Citation for the content below
      Histomorphometry on Regenerated Muscle Fiber in the Damaged Striated Muscle
      Ihwa Ŭidae chi. 1995;18(1):45-52.   Published online July 24, 2015
      Close
      Histomorphometry on Regenerated Muscle Fiber in the Damaged Striated Muscle
      Histomorphometry on Regenerated Muscle Fiber in the Damaged Striated Muscle
      TOP