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Right Ventricular Outflow Tract Reconstruction with Bovine and Porcine Composite Monocusp Valve in Swine Model

The Ewha Medical Journal 1997;20(1):77-82. Published online: July 24, 2015

Department of Thoracic and Cardiovascular Surgery, College of Medicine, Ewha Womans University, Korea.

Copyright © 1997. Ewha Womans University School of Medicine

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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  • Objective
    Rastelli procedure for right ventricular outflow tract(RVOT) obstruction has many disadvantage especially for children. Instead of using the artificial valved conduit, we applied the REV procedure for preventing the valve re-replacement after growing and observed the fate of that patch.
  • Method
    We performed REV procedure for RVOT reconstruction with our own hand-made monocusp patch composed of porcine pericardial cusp and bovine pericardial patch in 7 young piglets(15.3±1.3kg) and raised till adult pig9about 70 kg). After sacrificed the pig we explored their pulmonary arteries, monocusp patch and hearts.
  • Results
    Without any stenotic residues in the pulmonary artery, we found the deformed monocusp patch with severe calcification, which deprived the adequate valve function, but kept the pig growing normally.
  • Conclusion
    We are sure that this REV procedure with monocusp patch could be extendedly applied to the RVOT obstruction, but we need to develope the anti-calcification method for the heterograft patch.

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      Ihwa Ŭidae chi. 1997;20(1):77-82.   Published online July 24, 2015
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      Ihwa Ŭidae chi. 1997;20(1):77-82.   Published online July 24, 2015
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