The present study was performed to identify the dopaminergic receptor sites in rat amygdala. Identification of the receptor sites at ultrastructrual level has been done by autoradiography after cerebral ventricular perfusion of ³H-haloperidol.

From 434 examples of silver grains, 5% were labeled in soma, 36% in thick dendrites, 26% in the thin branches of axons and dendrites, 21% in thick axons and terminals and 12% in synapses with synaptic vesicles. In the cases of labeled synapses, all of axon terminals contained small round vesicles and showed asymmetric contact with dendrites. By these results it may be implied that dopamine receptors in the amygdala are located in both pre-and post-synaptic sites of the asymmetric axo-dendritic synapses with small round vesicles and the axons of labeled synapses originated from the dopaminergic neurons in the midbrain.

To evaluate the effect of BHA and BHT on liver tissue, BHA and BHT, 100mg and 200mg/kg B.W. respectively, were given to experimental animals for 4 months.

Microsomal cytochrome P-450, cytochrome b₅, cytochrome C reductase activity and lipid peroxidation of liver tissue of experimental animal were measured.

The results were as follow ;

1) Cytochrome P-450 increased significantly in experimental group given BHA but cytochrome b5 did not.

2) Cytochrome oxidnse activity increased moderately in BHA group but decreased in BHT group. From these finding, it can be assumed, that BHA and BHT has no great effect on human tissue.

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• Inhibition effect against elastase, collagenase, hyaluronidase and anti-oxidant activity of thinning Green ball apple
  Yu-Jin Go, Ye-Eun Kim, Hyun-Nam Kim, Eun-Ho Lee, Eun-Bi Cho, Akhmadjon Sultanov, Soon-Il Kwon, Young-Je Cho
  Journal of Applied Biological Chemistry.2020; 63(1): 43.     CrossRef

Mass screening of 827 faculty members in Ewha Womans University was conducted to examine prevalences of chronic diseases and usefulness of pre-questionnaire for detection of chronic diseases. The rate of unhealthy state among the participants was 6.7 per cent and was higher in male(10.7%), the older age group(13.2%), and the teaching staff(8.6%). Of the chronic diseases, diseases of the circulatory system were more highly detected. The results of health examination were in accord with the responses on pre-questionnaire for detection of chronic diseases in 65.2 per cent.

There were many instruments for the treatment of spondylolisthesis. Recently, the Cotrel-Dubousset system was introduced and it showed satisfactory stability and efficient reduction of displacement. Nine patients were treated with CD system at the department of orthopaedic surgery, college of Medicine, Ewha Womans University between October, 1987 and July, 1988. The results were as follows.

1) In 9 cases, 4 cases were male and 5 cases were female and age distribution was from 31 years old to 52 years old, the average was 41 years of age.

2) The displacement between L4 and L5 was observed in 5 cases and the degenerative type predominant.

3) The symptoms of back pain only was in 1 case, back pain and radiating pain in 4 cases back pain, radiating pain and neurological sign in 3 cases and radiating pain only in 1 case.

4) The amount of displacement measured by Boxall was from 12.7% preoperatively to 3.4% postoperatively and the amount of angle by Meschan was from 8.3 degrees preoperatively to 2.2 degrees postoperatively.

5) The overall results were satisfactory except 1 case.

The purpose of this experimental study is to determine the protective effect of pretreatment of mannitol, methylprednisolone, thiopental sodium and nimodipine against the acute focal cerebral ischemia. The energy metabolisms of the brain was measured utilizing the high liquid performance chromatography in the brain tissues of the cats. The experimental animals were separated into three groups. In group I (the sham control group) the middle cerebral artery(MCA) was not occluded. In group II (the recirculation group) the MCA was occluded for 5 hours and reperfused for 2 hours. In group III (the treatment group) the combinations of mannitol(2gm/kg), methylprednisolone(30mg/kg), and thiopental sodium(5mg/kg) were administered intravenously at 30 minutes before occlusion of the MCA. The mannitol and methylprednisolone were repeated every one and half hours and thiopental sodium every hours. Nimodipine(3µg/kg/min) was continuously intravenous infused during 7 hours, initiated 30minutes before induction of ischemia.

The experimental results are as follows.

1) Adenosine derivatives : In group III ATP and ADP were very highly signficantly increased to 485.35% and 218.45% respectively and the total adenylate to 170.27% of the value of group II. AMP reduced to 62.62% of the value of the group II.

2) Adenylate energy charge(E.C.) : In group III E.C. was increased to 196.67% of the value of group II and recoveried to 78.67% of the group I.

3) GTP and total guanylate : In group III GTP and total guanylate were very-highly signficantly increased to 351.55% and 241.22% of the value of the gorup II respectively.

4) UTP and total uridylate : In group III UTP and total uridylate were highly signficantly increased to 4296.30% and 222.22% of the value of the group II, respectively.

The above results suggest that the pretreatment of this therapeutic combination of the drugs may have an effective means of treating actue focal cerebral infarction and would be applicable in the clinical field in which the ischemia is anticipated during major cerebral artery occlusion.

Clinical analysis for 95 cases with spontaneous pneumothorax which were treated at the Department of Thoracic and Cardiovascular Surgery of Ewha Womans University Hospital from March, 1982 to February, 1988 had been done. Among 95 cases male was 81 and female was 14. Male to female ratio was 5.8:1. The youngest patient was 16 years old and the oldest was 73 years old. Most of the patients were between 21 and 40 years old. Ninety cases had unilateral pneumothorax and 5 cases had bilateral pneumothorax. Sudden dyspnea was appeared in 85.3% of all cases and chest pain was in 60% of patients. Initial treatment was bed rest with high oxygen therapy for 6 patients. Tube thoracostomy was done for the remaining cases. The results of initial treatment in 90 paients with unilateral pneumothorax as follow; Thoracotomy was done for 11 cases due to persistent air leak through the chest tube. initial treatment was sucessful in 79 cases but 22 cases were recurred. So recurrence rate was 27.8%. Among 22 cases, 13 cases were operated. There was no recurrence in thoracotomy cases. In 5 patients with bilateral pneumothorax, two cases were operated on one side. Bilateral thoracotomy was done for one patient.

The underlying causes of the spontaneous pneumothorax were bullae in 16 cases, bullae with pulmonary tuberculosis in 9 cases and pulmonary tuberculosis in 3 cases among 28 operations of 27 cases. Among 68 of non-thoracotomy patients, no definite causes were found in 31 cases and obstructive lung disease in 2 cases, lung cancer, lung abscess and pneumonia in 1 case each.

Relief of the pain is important for reducing patient's discomfort and morbidity after thoracotomy. Post-thoracotomy pain was controlled by pharmacological blockage of the intercostal nerves with bupivacaine in 20 patients. Bupivacaine was infused intermittently through one inwelling cathter, which was placed in the pleural space during the thoracotomy. Pain was well controlled by this procedure.

Acute scrotum is any pathologic condition of the scrotum or intrascrotal contents that requires emergency medical or surgical management. Among the acute scrotum acute epididymitis and spermatic cord torsion are most difficult to differentiate each other because of their similar symptoms and sings.

Clinical analysis was undertaken on 45 patients with acute epididymitis and spermatic cord torsion.

The following results were obtained.

1) There were 36 patients with acute epididymitis and 9 spermatic cord torsion.

2) Mean ages were 32.6 year old in acute epidiymitis and 12.5 spermatic cord torsion.

3) Symptoms and sings showed no significant differences from each other, but Prehn's sign was somewhat useful.

4) In 5 patients with spermatic cord torsion that had arrived to the hospital within 24 hours from onset of symptoms, the testis could be saved.

5) Testicular scan with 99mTc-pertechnetate was performed in 17 patients and the diagnostic accuracy was 94%.

6) Twenty-one patients with acute epididymitis had urinary tract infections and 3 spermatic cord torsion had cryptorchidisms.

We present two cases of pityriasis lichenoides et varioliformis acuta occurring on the whole body. The case 1 was a 13 year old male who have had papulosqamous, hemorrhagic lesions and were treated by tetracyclines. The other case was a 32 year old female who have had scaly erythematous papules and were treated by etretinates.

Pemphigus erythematosus(Senear-Usher syndrome) was originally described by Senear and Usher as a type of pemphigus with features of lupus erythematosus. We present two cases of pemphigus erythematosus on the face and trunk. The case 1 was a 41-year-old female who have had erythematous scaly patches and a few flaccid bullae, and treated by corticosteroids and azathioprine. The case 2 was a 42-year-old male who have had same lesions and treated by corticosterids.