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Volume 41(4); October 2018

Original Article

[English]
Clinical Observations of Kikuchi-Fujimoto Disease in Children and Adolescents: A Single Center Experience
Hee Won Kang, Han Wool Kim, Soyoung Lee, Kyung Ha Ryu, Hae Soon Kim, Eun Sun Yoo, Hee Jung Choi, Kyung-Hyo Kim
Ewha Med J 2018;41(4):75-81.   Published online October 29, 2018
DOI: https://doi.org/10.12771/emj.2018.41.4.75
Objectives

Kikuchi-Fujimoto disease (KFD) is characterized by lymphadenopathy and fever, and is usually self-limited. This study analyzed the clinical characteristics of pediatric patients with KFD.

Methods

This retrospective, observational, single-center study was conducted in South Korea from March 2008 to October 2015. KFD was diagnosed based on clinical, radiological or histological findings and excluded when there were any other causes of lymphadenopathy. Medical records were reviewed for clinical and laboratory manifestations.

Results

A total of 35 cases were included. The mean patient age was 12.1±2.9 years (range, 5 to 17 years); the male-to-female ratio was 1:0.8. The main clinical manifestations were cervical lymphadenopathy and fever in 34 cases (97%). The mean duration of fever was 12.2±8.3 days (range, 2 to 37 days). We noted enlargement of lymph nodes in the cervical, mesenteric (n=5, 14%), axillary (n=2, 6%), and inguinal (n=1, 3%) regions. Hepatosplenomegaly, loss of appetite, and rash were observed. On laboratory examinations, elevation of ferritin, leukopenia, and positivity for anti-nuclear antibodies were frequently observed. Twelve patients underwent biopsy and 23 cases were diagnosed by radiological findings. The mean duration of hospitalization for all cases was 7.9±2.9 days (range, 3 to 13 days) and steroids were administered in 10 cases. KFD recurrence was observed in 2 cases (5.7%) with the time to relapse of 7 months and 4 years. There were no cases with systemic lupus erythematous or other autoimmune disease.

Conclusion

KFD should be considered in pediatric patients with lymphadenopathy and prolonged fever. Patients with KFD should be monitored for recurrence and the development of autoimmune disease.

Citations

Citations to this article as recorded by  
  • Kikuchi-Fujimoto Disease Mimicking Mesenteric Lymphadenitis in Children: A Case Report and Systematic Review
    Gyeongseo Jeon, Si-Hwa Gwag, Young June Choe, Saelin Oh, Jun Eun Park
    Pediatric Infection & Vaccine.2023; 30(1): 39.     CrossRef
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  • 1 Crossref
Case Reports
[English]
Postherpetic Neuralgia Aggravated by Upper Complete Denture
Hyun Joo Heo, Yu Yil Kim, Ji Hye Lee, So Mang Im, Ok Hyun Kim, Han Gyeol Lee
Ewha Med J 2018;41(4):82-85.   Published online October 29, 2018
DOI: https://doi.org/10.12771/emj.2018.41.4.82

Postherpetic neuralgia (PHN) is a chronic and refractory pain disease. It requires longterm treatment and follow-up. Comorbid diseases can change or aggravate the pain condition and responsiveness of patients to PHN treatment. In such cases, the cause of pain should be identified through proper testing, and appropriate treatment should be administered. Herein, we report the case of a 67-year-old man with PHN in the maxillary nerve. As the pain was being controlled with medication and infraorbital nerve block, the patient experienced deterioration of pain caused by a newly worn upper complete denture. The patient's pain was relieved following correction of the upper complete denture.

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[English]
Endotracheal Intubation Using McGrath Videolaryngoscope in Klippel-Feil Syndrome
Ji Seon Chae, Jae Hee Woo, Chi Hyo Kim, Eun Hee Chun, Hee Jung Baik, Min Hee Choi
Ewha Med J 2018;41(4):86-89.   Published online October 29, 2018
DOI: https://doi.org/10.12771/emj.2018.41.4.86

Patients with Klippel-Feil syndrome require much attention during anesthesia because of congenital abnormalities in head and neck regions and the high probability of neurological damage from cervical spine instability during endotracheal intubation. We report a case of successful endotracheal intubation using a videolaryngoscope in a patient with Klippel-Feil syndrome who experienced difficult transnasal intubation.

Citations

Citations to this article as recorded by  
  • Perioperative Challenges in Airway and Ventilatory Management of a Neurosurgical Patient with Klippel–Feil Syndrome
    Geetha Lakshminarasimhaiah, Akshita Niranjan, Sonika Shivakumar
    Journal of Neuroanaesthesiology and Critical Care.2024; 11(01): 061.     CrossRef
  • 診療指針:困難気道管理の診療ガイドライン

    THE JOURNAL OF JAPAN SOCIETY FOR CLINICAL ANESTHESIA.2024; 44(1): 85.     CrossRef
  • 2022 American Society of Anesthesiologists Practice Guidelines for Management of the Difficult Airway *
    Jeffrey L. Apfelbaum, Carin A. Hagberg, Richard T. Connis, Basem B. Abdelmalak, Madhulika Agarkar, Richard P. Dutton, John E. Fiadjoe, Robert Greif, P. Allan Klock, David Mercier, Sheila N. Myatra, Ellen P. O’Sullivan, William H. Rosenblatt, Massimiliano
    Anesthesiology.2022; 136(1): 31.     CrossRef
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