Citations
The rate of colorectal cancer (CRC) has altered. Early-onset CRC patients are increasing, and it is one of the main causes of cancer-related death. Based on epidemiologic change, the CRC screening program needs to be changed. To increase compliance, non-invasive screening techniques are developed. Although CRC survival has increased, the oncologic prognosis of metastatic CRC is remains poor. Even in metastatic CRC, which is the most difficult to treat, attempts are being made to increase the survival rate by active surgical therapy with the creation of chemotherapeutic regimens and targeted treatment based on genomic information. Due to the introduction of aggressive chemotherapy regimens, targeted therapy based on genomic features, and improvements in surgical technique, the role of surgical treatment in metastatic CRC has expanded. Metastatic CRC surgery was indicated for liver, lung, and even peritoneal seeding. Local ablation therapy was also effectively used for liver and lung metastasis. Cytoreductive surgery and intraperitoneal chemotherapy were tried for peritoneal seeding and demonstrated good results in a subgroup of patients, although the right indication was carefully assessed. At the same time, one of the key goals of treatment for CRC was to maintain functional outcomes. Neoadjuvant treatment, in particular, helped rectal cancer patients preserve functional results while maintaining oncologic safety. Rectal cancer organ preservation techniques are now being researched heavily in a variety of neoadjuvant treatment settings, including immunotherapy and whole neoadjuvant therapy. Precision medicine based on patient and disease characteristics is currently being used for the diagnosis and treatment of CRC.
Citations
This study aimed at an examination of the item analysis and reliability of the Family screening test which was developed to assess the family's charateristics and the degree of family psychopathology from March 15 to May 30 1996
The subjects were 467 housewives who were sampled by the random sampling method in Seoul. This family screening test is composed of 11 subscales, the self-report measure, and a 5-point scale.
1) 98 items were selected by the item analysis and reliability evaluation among the original 1999 items which were categorized 11 subscales.
2) The internal consistency of the Cronbach's alpha and the speraman-Brown split-half correlation coefficients were more than 0.70 for all scales exept 8,9,10,11 scales.
3) The reliability coefficients of the Cronbach's alpha and the split-half correlation for 8,9,19,11 scales were less than 0.70 which were evaluated to have the insufficient corrected item-total correlation coefficients.
It was suggested that 8,9,10,11 scales need to the most items for increasing the reliability coefficients through the complemantary work.
, Gyoung Hee Kim This study was performed to investigate the prevalence of abnormal behavior, ada-ptability and intelligence of child and adolescents and the usefulness of KAS(Korean Attitude System) as a screening method to detect the psychopathology of child and adolescents.
478 child and adolescents were completed the instruments of KAS that focused on development of behavior, adaptability and intelligence at the children's medical examination center.
The most influenced subcategories to the disturbance of behavior of the subjects were leadership, cooperation, and emotion (in order). The preference of adaptability was high in the fields of literature, law, technology, medicine and sociology. The mean I.Q. of the subjects was high average and not different in both sex. The subjects with below average of I.Q. were three cases(0.6%) and the two of them were boderline and only one case was mild mental retardation. The total number of patients referred to the department of psychiatry was eight cases(1.7%) and revealed the disturbance of behavior, affect, and thought.
Finally the authors concluded that KAS test performed at the children's medical examination center was useful primary screening method to detect the psychopathology of child and adolescents.
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